Abstract 11. The Effect of Neoadjuvant Chemotherapy Compared to Adjuvant Chemotherapy in Nipple-Sparing Mastectomy

RESULTS: We identified 132 patients who underwent 186 abdominally based free flaps. 70 patients (104 breast reconstructions) had a prior history of abdominal surgery. 57 patients (73 breast reconstructions) had no prior abdominal surgeries. Five patients underwent simultaneous gynecologic surgery at the time of their free flap harvest; these patients were excluded from analysis. The groups were appropriately matched with respect to BMI, race/ethnicity, smoking status, and comorbidities. We found no difference in overall abdominal complications requiring surgical intervention (14.5% vs 15.8%, p= 0.84). Incidence of abdominal bulge was greater in the study group (11.4% vs 3.5%, p = 0.099), however this was not statistically significant. Breast related complications were also similar between the two groups. There were no total flap losses in either group. Rates of fat necrosis requiring excision were 15.4% vs 15.1%, p = 0.954.